Does DIPHENHYDRAMINE Cause Hepatotoxicity? 125 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 125 reports of Hepatotoxicity have been filed in association with DIPHENHYDRAMINE (Allergy Relief). This represents 0.5% of all adverse event reports for DIPHENHYDRAMINE.
125
Reports of Hepatotoxicity with DIPHENHYDRAMINE
0.5%
of all DIPHENHYDRAMINE reports
44
Deaths
95
Hospitalizations
How Dangerous Is Hepatotoxicity From DIPHENHYDRAMINE?
Of the 125 reports, 44 (35.2%) resulted in death, 95 (76.0%) required hospitalization, and 14 (11.2%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DIPHENHYDRAMINE. However, 125 reports have been filed with the FAERS database.
What Other Side Effects Does DIPHENHYDRAMINE Cause?
Toxicity to various agents (4,596)
Drug ineffective (3,511)
Completed suicide (3,081)
Off label use (2,639)
Fatigue (2,605)
Drug abuse (2,602)
Headache (2,171)
Overdose (2,082)
Pain (2,080)
Nausea (1,905)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DIPHENHYDRAMINE Alternatives Have Lower Hepatotoxicity Risk?
DIPHENHYDRAMINE vs DIPHENHYDRAMINE UNKNOWN PRODUCT
DIPHENHYDRAMINE vs DIPHENHYDRAMINE\IBUPROFEN
DIPHENHYDRAMINE vs DIPHENHYDRAMINE\NAPROXEN
DIPHENHYDRAMINE vs DIPHENOXYLATE
DIPHENHYDRAMINE vs DIPHTHERIA AND TETANUS TOXOIDS AND ACELLULAR PERTUSSIS ADSORBED AND INACTIVATED POLIOVIRUS VACCINE