Does DIVALPROEX Cause Hepatotoxicity? 126 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 126 reports of Hepatotoxicity have been filed in association with DIVALPROEX (Divalproex Sodium). This represents 1.1% of all adverse event reports for DIVALPROEX.
126
Reports of Hepatotoxicity with DIVALPROEX
1.1%
of all DIVALPROEX reports
5
Deaths
114
Hospitalizations
How Dangerous Is Hepatotoxicity From DIVALPROEX?
Of the 126 reports, 5 (4.0%) resulted in death, 114 (90.5%) required hospitalization, and 4 (3.2%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for DIVALPROEX.
What Other Side Effects Does DIVALPROEX Cause?
Drug ineffective (1,121)
Seizure (1,095)
Off label use (576)
Somnolence (545)
Drug interaction (540)
Nausea (526)
Weight increased (509)
Tremor (461)
Toxicity to various agents (452)
Vomiting (436)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DIVALPROEX Alternatives Have Lower Hepatotoxicity Risk?
DIVALPROEX vs DOBUTAMINE
DIVALPROEX vs DOBUTAMINE\DOBUTAMINE
DIVALPROEX vs DOCETAXEL
DIVALPROEX vs DOCETAXEL ANHYDROUS
DIVALPROEX vs DOCETAXEL\DOCETAXEL ANHYDROUS