Does DOLUTEGRAVIR Cause Hepatotoxicity? 79 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 79 reports of Hepatotoxicity have been filed in association with DOLUTEGRAVIR (Juluca). This represents 0.7% of all adverse event reports for DOLUTEGRAVIR.
79
Reports of Hepatotoxicity with DOLUTEGRAVIR
0.7%
of all DOLUTEGRAVIR reports
4
Deaths
23
Hospitalizations
How Dangerous Is Hepatotoxicity From DOLUTEGRAVIR?
Of the 79 reports, 4 (5.1%) resulted in death, 23 (29.1%) required hospitalization, and 10 (12.7%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for DOLUTEGRAVIR.
What Other Side Effects Does DOLUTEGRAVIR Cause?
Foetal exposure during pregnancy (1,036)
Exposure during pregnancy (776)
Virologic failure (770)
Pathogen resistance (586)
Maternal exposure during pregnancy (517)
Viral mutation identified (510)
Treatment failure (453)
Drug ineffective (447)
Off label use (413)
Blood hiv rna increased (410)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DOLUTEGRAVIR Alternatives Have Lower Hepatotoxicity Risk?
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE
DOLUTEGRAVIR vs DOLUTEGRAVIR\LAMIVUDINE\TENOFOVIR DISOPROXIL
DOLUTEGRAVIR vs DOLUTEGRAVIR\RILPIVIRINE
DOLUTEGRAVIR vs DOMPERIDONE
DOLUTEGRAVIR vs DOMPERIDONE\PANTOPRAZOLE