Does DOXORUBICIN Cause Hepatotoxicity? 468 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 468 reports of Hepatotoxicity have been filed in association with DOXORUBICIN (Doxorubicin Hydrochloride). This represents 0.6% of all adverse event reports for DOXORUBICIN.
468
Reports of Hepatotoxicity with DOXORUBICIN
0.6%
of all DOXORUBICIN reports
58
Deaths
132
Hospitalizations
How Dangerous Is Hepatotoxicity From DOXORUBICIN?
Of the 468 reports, 58 (12.4%) resulted in death, 132 (28.2%) required hospitalization, and 62 (13.2%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for DOXORUBICIN. However, 468 reports have been filed with the FAERS database.
What Other Side Effects Does DOXORUBICIN Cause?
Febrile neutropenia (8,844)
Off label use (7,858)
Disease progression (6,165)
Neutropenia (5,891)
Drug ineffective (4,598)
Pyrexia (3,697)
Thrombocytopenia (3,638)
Anaemia (3,601)
Product use in unapproved indication (3,502)
Nausea (2,925)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DOXORUBICIN Alternatives Have Lower Hepatotoxicity Risk?
DOXORUBICIN vs DOXYCYCLINE
DOXORUBICIN vs DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYCYCLINE\DOXYCYCLINE HYCLATE
DOXORUBICIN vs DOXYLAMINE
DOXORUBICIN vs DOXYLAMINE\PYRIDOXINE