Does DURVALUMAB Cause Hepatotoxicity? 29 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 29 reports of Hepatotoxicity have been filed in association with DURVALUMAB (IMFINZI). This represents 0.2% of all adverse event reports for DURVALUMAB.
29
Reports of Hepatotoxicity with DURVALUMAB
0.2%
of all DURVALUMAB reports
5
Deaths
6
Hospitalizations
How Dangerous Is Hepatotoxicity From DURVALUMAB?
Of the 29 reports, 5 (17.2%) resulted in death, 6 (20.7%) required hospitalization, and 1 (3.4%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for DURVALUMAB.
What Other Side Effects Does DURVALUMAB Cause?
Death (2,817)
Malignant neoplasm progression (1,330)
Pneumonitis (827)
Radiation pneumonitis (786)
Pyrexia (573)
Diarrhoea (530)
Pneumonia (453)
Dyspnoea (444)
Interstitial lung disease (430)
Off label use (395)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which DURVALUMAB Alternatives Have Lower Hepatotoxicity Risk?
DURVALUMAB vs DUTASTERIDE
DURVALUMAB vs DUTASTERIDE\TAMSULOSIN
DURVALUMAB vs DUVELISIB
DURVALUMAB vs DYDROGESTERONE
DURVALUMAB vs EBASTINE