Does FILGRASTIM Cause Hepatotoxicity? 82 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 82 reports of Hepatotoxicity have been filed in association with FILGRASTIM (NYPOZI txid). This represents 0.6% of all adverse event reports for FILGRASTIM.
82
Reports of Hepatotoxicity with FILGRASTIM
0.6%
of all FILGRASTIM reports
37
Deaths
26
Hospitalizations
How Dangerous Is Hepatotoxicity From FILGRASTIM?
Of the 82 reports, 37 (45.1%) resulted in death, 26 (31.7%) required hospitalization, and 30 (36.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for FILGRASTIM. However, 82 reports have been filed with the FAERS database.
What Other Side Effects Does FILGRASTIM Cause?
Off label use (1,930)
Febrile neutropenia (1,570)
Neutropenia (1,431)
Death (1,213)
Pyrexia (1,085)
Diarrhoea (739)
Nausea (718)
Bone pain (706)
Thrombocytopenia (697)
Anaemia (626)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which FILGRASTIM Alternatives Have Lower Hepatotoxicity Risk?
FILGRASTIM vs FILGRASTIM-AAFI
FILGRASTIM vs FILGRASTIM-SNDZ
FILGRASTIM vs FINASTERIDE
FILGRASTIM vs FINASTERIDE\TAMSULOSIN
FILGRASTIM vs FINERENONE