Does GEFITINIB Cause Hepatotoxicity? 56 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 56 reports of Hepatotoxicity have been filed in association with GEFITINIB (Gefitinib). This represents 1.2% of all adverse event reports for GEFITINIB.
56
Reports of Hepatotoxicity with GEFITINIB
1.2%
of all GEFITINIB reports
11
Deaths
9
Hospitalizations
How Dangerous Is Hepatotoxicity From GEFITINIB?
Of the 56 reports, 11 (19.6%) resulted in death, 9 (16.1%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for GEFITINIB.
What Other Side Effects Does GEFITINIB Cause?
Malignant neoplasm progression (1,651)
Drug resistance (1,228)
Death (590)
Diarrhoea (393)
Rash (318)
Metastases to central nervous system (306)
Acquired gene mutation (250)
Disease progression (244)
Drug ineffective (197)
Off label use (166)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which GEFITINIB Alternatives Have Lower Hepatotoxicity Risk?
GEFITINIB vs GELATIN
GEFITINIB vs GEMCITABINE
GEFITINIB vs GEMCITABINE\GEMCITABINE
GEFITINIB vs GEMFIBROZIL
GEFITINIB vs GEMTUZUMAB OZOGAMICIN