Does GEMCITABINE Cause Hepatotoxicity? 202 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 202 reports of Hepatotoxicity have been filed in association with GEMCITABINE (Gemcitabine). This represents 0.6% of all adverse event reports for GEMCITABINE.
202
Reports of Hepatotoxicity with GEMCITABINE
0.6%
of all GEMCITABINE reports
34
Deaths
45
Hospitalizations
How Dangerous Is Hepatotoxicity From GEMCITABINE?
Of the 202 reports, 34 (16.8%) resulted in death, 45 (22.3%) required hospitalization, and 17 (8.4%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GEMCITABINE. However, 202 reports have been filed with the FAERS database.
What Other Side Effects Does GEMCITABINE Cause?
Off label use (3,319)
Disease progression (3,123)
Thrombocytopenia (2,320)
Drug ineffective (2,003)
Malignant neoplasm progression (1,962)
Neutropenia (1,892)
Anaemia (1,745)
Pyrexia (1,511)
Nausea (1,336)
Myelosuppression (1,197)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which GEMCITABINE Alternatives Have Lower Hepatotoxicity Risk?
GEMCITABINE vs GEMCITABINE\GEMCITABINE
GEMCITABINE vs GEMFIBROZIL
GEMCITABINE vs GEMTUZUMAB OZOGAMICIN
GEMCITABINE vs GEMZAR
GEMCITABINE vs GENTAMICIN