Does GILTERITINIB Cause Hepatotoxicity? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Hepatotoxicity have been filed in association with GILTERITINIB (Xospata). This represents 1.0% of all adverse event reports for GILTERITINIB.
35
Reports of Hepatotoxicity with GILTERITINIB
1.0%
of all GILTERITINIB reports
3
Deaths
4
Hospitalizations
How Dangerous Is Hepatotoxicity From GILTERITINIB?
Of the 35 reports, 3 (8.6%) resulted in death, 4 (11.4%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GILTERITINIB. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does GILTERITINIB Cause?
Acute myeloid leukaemia (366)
Febrile neutropenia (346)
Off label use (334)
Platelet count decreased (327)
Pneumonia (302)
Myelosuppression (300)
Pyrexia (281)
Death (206)
Product use issue (189)
Hepatic function abnormal (181)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which GILTERITINIB Alternatives Have Lower Hepatotoxicity Risk?
GILTERITINIB vs GIMERACIL\OTERACIL\TEGAFUR
GILTERITINIB vs GINKGO
GILTERITINIB vs GIVINOSTAT
GILTERITINIB vs GIVOSIRAN
GILTERITINIB vs GLASDEGIB