Does GOLIMUMAB Cause Hepatotoxicity? 253 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 253 reports of Hepatotoxicity have been filed in association with GOLIMUMAB (SIMPONI ARIA). This represents 0.4% of all adverse event reports for GOLIMUMAB.
253
Reports of Hepatotoxicity with GOLIMUMAB
0.4%
of all GOLIMUMAB reports
19
Deaths
112
Hospitalizations
How Dangerous Is Hepatotoxicity From GOLIMUMAB?
Of the 253 reports, 19 (7.5%) resulted in death, 112 (44.3%) required hospitalization, and 20 (7.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for GOLIMUMAB. However, 253 reports have been filed with the FAERS database.
What Other Side Effects Does GOLIMUMAB Cause?
Drug ineffective (17,959)
Rheumatoid arthritis (12,272)
Pain (11,443)
Fatigue (9,626)
Off label use (8,764)
Alopecia (8,394)
Rash (8,331)
Joint swelling (8,264)
Arthralgia (7,968)
Abdominal discomfort (7,902)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which GOLIMUMAB Alternatives Have Lower Hepatotoxicity Risk?
GOLIMUMAB vs GOLODIRSEN
GOLIMUMAB vs GONADORELIN
GOLIMUMAB vs GONADOTROPHIN, CHORIONIC
GOLIMUMAB vs GOSERELIN
GOLIMUMAB vs GRAMICIDIN