Does IFOSFAMIDE Cause Hepatotoxicity? 88 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 88 reports of Hepatotoxicity have been filed in association with IFOSFAMIDE (IFEX). This represents 0.5% of all adverse event reports for IFOSFAMIDE.
88
Reports of Hepatotoxicity with IFOSFAMIDE
0.5%
of all IFOSFAMIDE reports
35
Deaths
26
Hospitalizations
How Dangerous Is Hepatotoxicity From IFOSFAMIDE?
Of the 88 reports, 35 (39.8%) resulted in death, 26 (29.5%) required hospitalization, and 21 (23.9%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for IFOSFAMIDE.
What Other Side Effects Does IFOSFAMIDE Cause?
Off label use (2,281)
Febrile neutropenia (2,225)
Disease progression (1,912)
Neutropenia (1,509)
Drug ineffective (1,331)
Thrombocytopenia (1,227)
Anaemia (1,067)
Product use in unapproved indication (890)
Pyrexia (752)
Sepsis (712)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which IFOSFAMIDE Alternatives Have Lower Hepatotoxicity Risk?
IFOSFAMIDE vs IGURATIMOD
IFOSFAMIDE vs ILOPERIDONE
IFOSFAMIDE vs ILOPROST
IFOSFAMIDE vs IMATINIB
IFOSFAMIDE vs IMBRUVICA