Does INFLIXIMAB Cause Hepatotoxicity? 316 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 316 reports of Hepatotoxicity have been filed in association with INFLIXIMAB (Renflexis). This represents 0.2% of all adverse event reports for INFLIXIMAB.
316
Reports of Hepatotoxicity with INFLIXIMAB
0.2%
of all INFLIXIMAB reports
26
Deaths
72
Hospitalizations
How Dangerous Is Hepatotoxicity From INFLIXIMAB?
Of the 316 reports, 26 (8.2%) resulted in death, 72 (22.8%) required hospitalization, and 21 (6.6%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for INFLIXIMAB.
What Other Side Effects Does INFLIXIMAB Cause?
Off label use (34,801)
Drug ineffective (33,738)
Condition aggravated (16,616)
Rheumatoid arthritis (16,251)
Pain (15,061)
Fatigue (13,473)
Arthralgia (13,441)
Infusion related reaction (12,946)
Product use issue (12,752)
Drug intolerance (11,173)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which INFLIXIMAB Alternatives Have Lower Hepatotoxicity Risk?
INFLIXIMAB vs INFLIXIMAB-ABDA
INFLIXIMAB vs INFLIXIMAB-AXXQ
INFLIXIMAB vs INFLIXIMAB-DYYB
INFLIXIMAB vs INFLIXIMAB-QBTX
INFLIXIMAB vs INFLIXIMAB, RECOMBINANT