Does IPILIMUMAB Cause Hepatotoxicity? 234 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 234 reports of Hepatotoxicity have been filed in association with IPILIMUMAB (YERVOY). This represents 0.6% of all adverse event reports for IPILIMUMAB.
234
Reports of Hepatotoxicity with IPILIMUMAB
0.6%
of all IPILIMUMAB reports
28
Deaths
113
Hospitalizations
How Dangerous Is Hepatotoxicity From IPILIMUMAB?
Of the 234 reports, 28 (12.0%) resulted in death, 113 (48.3%) required hospitalization, and 17 (7.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for IPILIMUMAB.
What Other Side Effects Does IPILIMUMAB Cause?
Death (3,710)
Malignant neoplasm progression (3,296)
Diarrhoea (2,557)
Off label use (2,097)
Colitis (1,988)
Pyrexia (1,796)
Rash (1,556)
Fatigue (1,447)
Intentional product use issue (1,329)
Nausea (1,169)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which IPILIMUMAB Alternatives Have Lower Hepatotoxicity Risk?
IPILIMUMAB vs IPRAGLIFLOZIN L-PROLINE
IPILIMUMAB vs IPRATROPIUM
IPILIMUMAB vs IPRATROPIUM\IPRATROPIUM ANHYDROUS
IPILIMUMAB vs IPTACOPAN
IPILIMUMAB vs IRBESARTAN