Does ISONIAZID Cause Agranulocytosis? 23 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 23 reports of Agranulocytosis have been filed in association with ISONIAZID (Isoniazid). This represents 0.3% of all adverse event reports for ISONIAZID.
23
Reports of Agranulocytosis with ISONIAZID
0.3%
of all ISONIAZID reports
0
Deaths
15
Hospitalizations
How Dangerous Is Agranulocytosis From ISONIAZID?
Of the 23 reports, 15 (65.2%) required hospitalization, and 1 (4.3%) were considered life-threatening.
Is Agranulocytosis Listed in the Official Label?
Yes, Agranulocytosis is listed as a known adverse reaction in the official FDA drug label for ISONIAZID.
What Other Side Effects Does ISONIAZID Cause?
Drug-induced liver injury (766)
Drug ineffective (607)
Drug reaction with eosinophilia and systemic symptoms (550)
Pyrexia (517)
Nausea (488)
Paradoxical drug reaction (433)
Off label use (406)
Drug resistance (367)
Hepatotoxicity (349)
Headache (324)
What Other Drugs Cause Agranulocytosis?
CLOZAPINE (1,766)
CYCLOPHOSPHAMIDE (1,242)
RITUXIMAB (1,154)
SULFAMETHOXAZOLE\TRIMETHOPRIM (797)
PANTOPRAZOLE (599)
METHOTREXATE (550)
SODIUM (549)
EPIRUBICIN (491)
METAMIZOLE (438)
DOCETAXEL (436)
Which ISONIAZID Alternatives Have Lower Agranulocytosis Risk?
ISONIAZID vs ISONIAZID\PYRAZINAMIDE\RIFAMPIN
ISONIAZID vs ISONIAZID\PYRIDOXINE\SULFAMETHOXAZOLE\TRIMETHOPRIM
ISONIAZID vs ISONIAZID\RIFAMPIN
ISONIAZID vs ISOPROPANOLAMINE
ISONIAZID vs ISOPROPYL ALCOHOL