Does LETROZOLE Cause Hepatotoxicity? 416 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 416 reports of Hepatotoxicity have been filed in association with LETROZOLE (Letrozole). This represents 1.3% of all adverse event reports for LETROZOLE.
416
Reports of Hepatotoxicity with LETROZOLE
1.3%
of all LETROZOLE reports
29
Deaths
80
Hospitalizations
How Dangerous Is Hepatotoxicity From LETROZOLE?
Of the 416 reports, 29 (7.0%) resulted in death, 80 (19.2%) required hospitalization, and 51 (12.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LETROZOLE. However, 416 reports have been filed with the FAERS database.
What Other Side Effects Does LETROZOLE Cause?
Neutropenia (3,683)
Fatigue (3,568)
Malignant neoplasm progression (3,445)
Nausea (2,894)
Arthralgia (2,318)
Diarrhoea (2,282)
Metastases to bone (1,735)
Dyspnoea (1,621)
Asthenia (1,589)
Vomiting (1,560)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which LETROZOLE Alternatives Have Lower Hepatotoxicity Risk?
LETROZOLE vs LETROZOLE\RIBOCICLIB
LETROZOLE vs LEUCOVORIN
LETROZOLE vs LEUCOVORIN\LEUCOVORIN
LETROZOLE vs LEUPROLIDE
LETROZOLE vs LEVALBUTEROL