Does LEVETIRACETAM Cause Hyperammonaemia? 192 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 192 reports of Hyperammonaemia have been filed in association with LEVETIRACETAM (Levetiracetam). This represents 0.3% of all adverse event reports for LEVETIRACETAM.
192
Reports of Hyperammonaemia with LEVETIRACETAM
0.3%
of all LEVETIRACETAM reports
18
Deaths
67
Hospitalizations
How Dangerous Is Hyperammonaemia From LEVETIRACETAM?
Of the 192 reports, 18 (9.4%) resulted in death, 67 (34.9%) required hospitalization, and 18 (9.4%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for LEVETIRACETAM. However, 192 reports have been filed with the FAERS database.
What Other Side Effects Does LEVETIRACETAM Cause?
Seizure (9,961)
Drug ineffective (8,666)
Off label use (5,789)
Maternal exposure during pregnancy (3,197)
Foetal exposure during pregnancy (2,604)
Epilepsy (2,546)
Generalised tonic-clonic seizure (2,276)
Somnolence (2,070)
Fatigue (1,972)
Status epilepticus (1,883)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
TACROLIMUS (181)
ACETAMINOPHEN (177)
OXALIPLATIN (160)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
METHOTREXATE (126)
Which LEVETIRACETAM Alternatives Have Lower Hyperammonaemia Risk?
LEVETIRACETAM vs LEVOBUNOLOL
LEVETIRACETAM vs LEVOBUPIVACAINE
LEVETIRACETAM vs LEVOCARNITINE
LEVETIRACETAM vs LEVOCETIRIZINE
LEVETIRACETAM vs LEVODOPA