Does OXALIPLATIN Cause Hyperammonaemia? 160 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 160 reports of Hyperammonaemia have been filed in association with OXALIPLATIN (Oxaliplatin). This represents 0.3% of all adverse event reports for OXALIPLATIN.
160
Reports of Hyperammonaemia with OXALIPLATIN
0.3%
of all OXALIPLATIN reports
8
Deaths
84
Hospitalizations
How Dangerous Is Hyperammonaemia From OXALIPLATIN?
Of the 160 reports, 8 (5.0%) resulted in death, 84 (52.5%) required hospitalization, and 35 (21.9%) were considered life-threatening.
Is Hyperammonaemia Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for OXALIPLATIN. However, 160 reports have been filed with the FAERS database.
What Other Side Effects Does OXALIPLATIN Cause?
Diarrhoea (4,963)
Nausea (4,250)
Neuropathy peripheral (3,662)
Off label use (3,603)
Neutropenia (3,391)
Vomiting (3,383)
Disease progression (3,370)
Thrombocytopenia (2,886)
Dyspnoea (2,779)
Pyrexia (2,269)
What Other Drugs Cause Hyperammonaemia?
VALPROIC ACID (581)
VALPROATE (328)
FLUOROURACIL (263)
DIVALPROEX (256)
LEVETIRACETAM (192)
TACROLIMUS (181)
ACETAMINOPHEN (177)
TOPIRAMATE (156)
GLYCEROL PHENYLBUTYRATE (147)
METHOTREXATE (126)
Which OXALIPLATIN Alternatives Have Lower Hyperammonaemia Risk?
OXALIPLATIN vs OXAPROZIN
OXALIPLATIN vs OXAZEPAM
OXALIPLATIN vs OXCARBAZEPINE
OXALIPLATIN vs OXITRIPTAN
OXALIPLATIN vs OXOMEMAZINE