Does LORLATINIB Cause Hepatotoxicity? 15 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 15 reports of Hepatotoxicity have been filed in association with LORLATINIB (Lorbrena). This represents 0.3% of all adverse event reports for LORLATINIB.
15
Reports of Hepatotoxicity with LORLATINIB
0.3%
of all LORLATINIB reports
2
Deaths
2
Hospitalizations
How Dangerous Is Hepatotoxicity From LORLATINIB?
Of the 15 reports, 2 (13.3%) resulted in death, 2 (13.3%) required hospitalization.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for LORLATINIB.
What Other Side Effects Does LORLATINIB Cause?
Death (1,050)
Neoplasm progression (633)
Off label use (394)
Weight increased (306)
Hallucination (290)
Blood cholesterol increased (281)
Dyspnoea (223)
Oedema peripheral (198)
Oedema (195)
Fatigue (188)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which LORLATINIB Alternatives Have Lower Hepatotoxicity Risk?
LORLATINIB vs LORMETAZEPAM
LORLATINIB vs LORNOXICAM
LORLATINIB vs LOSARTAN
LORLATINIB vs LOSARTAN\LOSARTAN
LORLATINIB vs LOTEPREDNOL ETABONATE