Does MELPHALAN Cause Acute hepatic failure? 35 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 35 reports of Acute hepatic failure have been filed in association with MELPHALAN (Melphalan Hydrochloride). This represents 0.2% of all adverse event reports for MELPHALAN.
35
Reports of Acute hepatic failure with MELPHALAN
0.2%
of all MELPHALAN reports
33
Deaths
20
Hospitalizations
How Dangerous Is Acute hepatic failure From MELPHALAN?
Of the 35 reports, 33 (94.3%) resulted in death, 20 (57.1%) required hospitalization, and 8 (22.9%) were considered life-threatening.
Is Acute hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MELPHALAN. However, 35 reports have been filed with the FAERS database.
What Other Side Effects Does MELPHALAN Cause?
Off label use (2,002)
Febrile neutropenia (931)
Drug ineffective (853)
Neutropenia (810)
Mucosal inflammation (804)
Plasma cell myeloma (781)
Product use in unapproved indication (765)
Thrombocytopenia (701)
Diarrhoea (698)
Pyrexia (667)
What Other Drugs Cause Acute hepatic failure?
ACETAMINOPHEN (3,141)
PREDNISONE (439)
IBUPROFEN (412)
RITUXIMAB (412)
CYCLOPHOSPHAMIDE (411)
DOXORUBICIN (385)
VINCRISTINE (346)
PREDNISOLONE (301)
METHOTREXATE (285)
DEXAMETHASONE (249)
Which MELPHALAN Alternatives Have Lower Acute hepatic failure Risk?
MELPHALAN vs MEMANTINE
MELPHALAN vs MENINGOCOCCAL GROUP B VACCINE
MELPHALAN vs MENINGOCOCCAL POLYSACCHARIDE VACCINE A\NEISSERIA MENINGITIDIS GROUP A CAPSULAR POLYSACCHARIDE ANTIGEN
MELPHALAN vs MENOTROPINS
MELPHALAN vs MENTHOL