Does MERCAPTOPURINE Cause Hepatotoxicity? 213 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 213 reports of Hepatotoxicity have been filed in association with MERCAPTOPURINE (Mercaptopurine). This represents 1.9% of all adverse event reports for MERCAPTOPURINE.
213
Reports of Hepatotoxicity with MERCAPTOPURINE
1.9%
of all MERCAPTOPURINE reports
24
Deaths
68
Hospitalizations
How Dangerous Is Hepatotoxicity From MERCAPTOPURINE?
Of the 213 reports, 24 (11.3%) resulted in death, 68 (31.9%) required hospitalization, and 24 (11.3%) were considered life-threatening.
Is Hepatotoxicity Listed in the Official Label?
Yes, Hepatotoxicity is listed as a known adverse reaction in the official FDA drug label for MERCAPTOPURINE.
What Other Side Effects Does MERCAPTOPURINE Cause?
Febrile neutropenia (1,853)
Off label use (893)
Pyrexia (855)
Drug ineffective (721)
Vomiting (488)
Neutropenia (485)
Nausea (418)
Pneumonia (394)
Pancytopenia (392)
Sepsis (389)
What Other Drugs Cause Hepatotoxicity?
METHOTREXATE (1,917)
ACETAMINOPHEN (1,557)
LEFLUNOMIDE (829)
HYDROXYCHLOROQUINE (715)
PREDNISONE (707)
RITUXIMAB (702)
ETANERCEPT (699)
ADALIMUMAB (674)
CYCLOPHOSPHAMIDE (632)
SULFASALAZINE (613)
Which MERCAPTOPURINE Alternatives Have Lower Hepatotoxicity Risk?
MERCAPTOPURINE vs MEROPENEM
MERCAPTOPURINE vs MEROPENEM ANHYDROUS
MERCAPTOPURINE vs MESALAMINE
MERCAPTOPURINE vs MESNA
MERCAPTOPURINE vs METAMIZOLE