Does MESNA Cause Hepatic failure? 12 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 12 reports of Hepatic failure have been filed in association with MESNA (mesna). This represents 0.3% of all adverse event reports for MESNA.
12
Reports of Hepatic failure with MESNA
0.3%
of all MESNA reports
12
Deaths
5
Hospitalizations
How Dangerous Is Hepatic failure From MESNA?
Of the 12 reports, 12 (100.0%) resulted in death, 5 (41.7%) required hospitalization, and 3 (25.0%) were considered life-threatening.
Is Hepatic failure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for MESNA. However, 12 reports have been filed with the FAERS database.
What Other Side Effects Does MESNA Cause?
Febrile neutropenia (707)
Pyrexia (352)
Off label use (299)
Cystitis haemorrhagic (294)
Disease progression (273)
Neutropenia (238)
Encephalopathy (226)
Vomiting (200)
Death (184)
Pancytopenia (179)
What Other Drugs Cause Hepatic failure?
ACETAMINOPHEN (1,392)
RIBAVIRIN (888)
CYCLOPHOSPHAMIDE (629)
METHOTREXATE (598)
BEVACIZUMAB (558)
SOFOSBUVIR (525)
RITUXIMAB (513)
VINCRISTINE (468)
DOXORUBICIN (462)
PREDNISOLONE (425)
Which MESNA Alternatives Have Lower Hepatic failure Risk?
MESNA vs METAMIZOLE
MESNA vs METARAMINOL
MESNA vs METAXALONE
MESNA vs METFORMIN
MESNA vs METFORMIN\PIOGLITAZONE