Does METHOTREXATE Cause Alanine aminotransferase increased? 2,440 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 2,440 reports of Alanine aminotransferase increased have been filed in association with METHOTREXATE (Methotrexate). This represents 1.0% of all adverse event reports for METHOTREXATE.
2,440
Reports of Alanine aminotransferase increased with METHOTREXATE
1.0%
of all METHOTREXATE reports
70
Deaths
1,095
Hospitalizations
How Dangerous Is Alanine aminotransferase increased From METHOTREXATE?
Of the 2,440 reports, 70 (2.9%) resulted in death, 1,095 (44.9%) required hospitalization, and 105 (4.3%) were considered life-threatening.
Is Alanine aminotransferase increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 2,440 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Alanine aminotransferase increased?
RITUXIMAB (1,651)
ADALIMUMAB (1,308)
TOCILIZUMAB (1,163)
ETANERCEPT (1,131)
LEFLUNOMIDE (1,099)
ACETAMINOPHEN (1,083)
REMDESIVIR (1,047)
FINGOLIMOD (1,020)
INFLIXIMAB (981)
HYDROXYCHLOROQUINE (925)
Which METHOTREXATE Alternatives Have Lower Alanine aminotransferase increased Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA