Alanine aminotransferase increased: Which Medications Cause It? (35,222 Reports Across 1,168 Drugs)
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Alanine aminotransferase increased has been reported as an adverse event with 1,168 different drugs in the FDA's FAERS database, with 35,222 total reports. 2,710 of these reports resulted in death.The drugs most commonly associated with Alanine aminotransferase increased are METHOTREXATE, RITUXIMAB, and ADALIMUMAB.
35,222
Total Reports
1,168
Drugs Involved
2,710
Deaths
12,893
Hospitalizations
50.4 yrs
Average Patient Age
55.2% / 44.8%
Female / Male
Which Drugs Cause Alanine aminotransferase increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METHOTREXATE | 2,440 | 1.0% | 70 | 1,095 | 105 |
| RITUXIMAB | 1,651 | 0.9% | 101 | 855 | 88 |
| ADALIMUMAB | 1,308 | 0.3% | 27 | 767 | 44 |
| TOCILIZUMAB | 1,163 | 1.2% | 34 | 683 | 45 |
| ETANERCEPT | 1,131 | 0.3% | 11 | 625 | 49 |
| LEFLUNOMIDE | 1,099 | 1.9% | 1 | 646 | 27 |
| ACETAMINOPHEN | 1,083 | 0.8% | 83 | 765 | 170 |
| REMDESIVIR | 1,047 | 10.0% | 72 | 114 | 28 |
| FINGOLIMOD | 1,020 | 1.4% | 8 | 170 | 26 |
| INFLIXIMAB | 981 | 0.7% | 11 | 651 | 29 |
| HYDROXYCHLOROQUINE | 925 | 1.4% | 13 | 608 | 28 |
| SULFASALAZINE | 848 | 2.1% | 2 | 575 | 23 |
| CYCLOPHOSPHAMIDE | 833 | 0.7% | 86 | 286 | 67 |
| ABATACEPT | 826 | 0.7% | 1 | 594 | 25 |
| PREDNISONE | 814 | 0.5% | 69 | 286 | 82 |
| RIBOCICLIB | 786 | 2.8% | 66 | 198 | 99 |
| NIVOLUMAB | 755 | 0.9% | 164 | 482 | 106 |
| PACLITAXEL | 725 | 0.9% | 109 | 272 | 35 |
| PEMBROLIZUMAB | 725 | 0.9% | 87 | 342 | 42 |
| CARBOPLATIN | 718 | 0.9% | 64 | 314 | 60 |