Does METHOTREXATE Cause Central nervous system lesion? 147 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 147 reports of Central nervous system lesion have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
147
Reports of Central nervous system lesion with METHOTREXATE
0.1%
of all METHOTREXATE reports
18
Deaths
64
Hospitalizations
How Dangerous Is Central nervous system lesion From METHOTREXATE?
Of the 147 reports, 18 (12.2%) resulted in death, 64 (43.5%) required hospitalization, and 15 (10.2%) were considered life-threatening.
Is Central nervous system lesion Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 147 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Central nervous system lesion?
FINGOLIMOD (2,416)
DIMETHYL (1,152)
INTERFERON BETA-1A (978)
NATALIZUMAB (627)
DALFAMPRIDINE (561)
GLATIRAMER (492)
TERIFLUNOMIDE (315)
ADALIMUMAB (229)
OFATUMUMAB (185)
RITUXIMAB (151)
Which METHOTREXATE Alternatives Have Lower Central nervous system lesion Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA