Central nervous system lesion: Which Medications Cause It? (10,290 Reports Across 364 Drugs)
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Central nervous system lesion has been reported as an adverse event with 364 different drugs in the FDA's FAERS database, with 10,290 total reports. 496 of these reports resulted in death.The drugs most commonly associated with Central nervous system lesion are FINGOLIMOD, DIMETHYL, and INTERFERON BETA-1A.
10,290
Total Reports
364
Drugs Involved
496
Deaths
2,913
Hospitalizations
45.6 yrs
Average Patient Age
70.9% / 29.1%
Female / Male
Which Drugs Cause Central nervous system lesion Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| FINGOLIMOD | 2,416 | 3.4% | 22 | 437 | 48 |
| DIMETHYL | 1,152 | 1.2% | 5 | 270 | 3 |
| INTERFERON BETA-1A | 978 | 1.5% | 3 | 185 | 3 |
| NATALIZUMAB | 627 | 1.0% | 13 | 211 | 6 |
| DALFAMPRIDINE | 561 | 1.0% | 12 | 133 | 3 |
| GLATIRAMER | 492 | 1.1% | 2 | 35 | 0 |
| TERIFLUNOMIDE | 315 | 0.8% | 3 | 81 | 3 |
| ADALIMUMAB | 229 | 0.1% | 16 | 80 | 6 |
| OFATUMUMAB | 185 | 0.6% | 1 | 28 | 1 |
| RITUXIMAB | 151 | 0.1% | 17 | 76 | 11 |
| METHOTREXATE | 147 | 0.1% | 18 | 64 | 15 |
| PREDNISONE | 139 | 0.1% | 43 | 83 | 27 |
| BACLOFEN | 124 | 0.5% | 1 | 10 | 1 |
| TACROLIMUS | 122 | 0.1% | 38 | 98 | 31 |
| DEXAMETHASONE | 117 | 0.1% | 30 | 57 | 14 |
| TYSABRI | 116 | 1.4% | 1 | 17 | 1 |
| GABAPENTIN | 113 | 0.2% | 2 | 5 | 0 |
| CYCLOPHOSPHAMIDE | 108 | 0.1% | 12 | 44 | 4 |
| SIPONIMOD | 108 | 1.3% | 1 | 8 | 0 |
| GILENYA | 107 | 6.4% | 4 | 30 | 3 |