Does METHOTREXATE Cause Drug level increased? 528 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 528 reports of Drug level increased have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
528
Reports of Drug level increased with METHOTREXATE
0.2%
of all METHOTREXATE reports
29
Deaths
326
Hospitalizations
How Dangerous Is Drug level increased From METHOTREXATE?
Of the 528 reports, 29 (5.5%) resulted in death, 326 (61.7%) required hospitalization, and 93 (17.6%) were considered life-threatening.
Is Drug level increased Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 528 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Drug level increased?
TACROLIMUS (1,013)
METFORMIN (886)
CLOZAPINE (554)
LAMOTRIGINE (541)
ACETAMINOPHEN (538)
VANCOMYCIN (447)
AMLODIPINE (329)
VORICONAZOLE (325)
OLANZAPINE (283)
MYCOPHENOLATE MOFETIL (277)
Which METHOTREXATE Alternatives Have Lower Drug level increased Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA