Drug level increased: Which Medications Cause It? (11,356 Reports Across 538 Drugs)
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Drug level increased has been reported as an adverse event with 538 different drugs in the FDA's FAERS database, with 11,356 total reports. 1,186 of these reports resulted in death.The drugs most commonly associated with Drug level increased are TACROLIMUS, METFORMIN, and CLOZAPINE.
11,356
Total Reports
538
Drugs Involved
1,186
Deaths
5,919
Hospitalizations
49.5 yrs
Average Patient Age
51.6% / 48.4%
Female / Male
Which Drugs Cause Drug level increased Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TACROLIMUS | 1,013 | 1.1% | 58 | 553 | 100 |
| METFORMIN | 886 | 1.0% | 200 | 691 | 335 |
| CLOZAPINE | 554 | 0.6% | 35 | 247 | 20 |
| LAMOTRIGINE | 541 | 1.1% | 12 | 146 | 23 |
| ACETAMINOPHEN | 538 | 0.4% | 54 | 352 | 101 |
| METHOTREXATE | 528 | 0.2% | 29 | 326 | 93 |
| VANCOMYCIN | 447 | 1.3% | 27 | 253 | 30 |
| AMLODIPINE | 329 | 0.5% | 52 | 118 | 62 |
| VORICONAZOLE | 325 | 2.3% | 32 | 118 | 24 |
| OLANZAPINE | 283 | 0.6% | 29 | 100 | 22 |
| MYCOPHENOLATE MOFETIL | 277 | 0.4% | 16 | 164 | 10 |
| VALPROIC ACID | 265 | 1.3% | 8 | 133 | 26 |
| ARIPIPRAZOLE | 263 | 0.4% | 12 | 83 | 10 |
| QUETIAPINE | 246 | 0.3% | 47 | 176 | 72 |
| DIVALPROEX | 243 | 2.1% | 5 | 111 | 16 |
| INFLIXIMAB | 228 | 0.2% | 1 | 59 | 3 |
| ZOPICLONE | 212 | 1.5% | 30 | 49 | 18 |
| LEVETIRACETAM | 208 | 0.3% | 9 | 145 | 14 |
| SERTRALINE | 193 | 0.3% | 88 | 71 | 17 |
| INFLIXIMAB-DYYB | 177 | 0.7% | 1 | 53 | 0 |