Does METHOTREXATE Cause Facet joint syndrome? 1,483 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 1,483 reports of Facet joint syndrome have been filed in association with METHOTREXATE (Methotrexate). This represents 0.6% of all adverse event reports for METHOTREXATE.
1,483
Reports of Facet joint syndrome with METHOTREXATE
0.6%
of all METHOTREXATE reports
1,300
Deaths
1,306
Hospitalizations
How Dangerous Is Facet joint syndrome From METHOTREXATE?
Of the 1,483 reports, 1,300 (87.7%) resulted in death, 1,306 (88.1%) required hospitalization, and 1,304 (87.9%) were considered life-threatening.
Is Facet joint syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 1,483 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Facet joint syndrome?
RITUXIMAB (1,497)
TOCILIZUMAB (1,467)
LEFLUNOMIDE (1,464)
DICLOFENAC (1,441)
ALENDRONATE (1,425)
SECUKINUMAB (1,420)
ABATACEPT (1,410)
ADALIMUMAB (1,377)
FOLIC ACID (1,346)
CETIRIZINE (1,337)
Which METHOTREXATE Alternatives Have Lower Facet joint syndrome Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA