Does METHOTREXATE Cause Gastric perforation? 42 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 42 reports of Gastric perforation have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
42
Reports of Gastric perforation with METHOTREXATE
0.0%
of all METHOTREXATE reports
2
Deaths
12
Hospitalizations
How Dangerous Is Gastric perforation From METHOTREXATE?
Of the 42 reports, 2 (4.8%) resulted in death, 12 (28.6%) required hospitalization.
Is Gastric perforation Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 42 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Gastric perforation?
IBUPROFEN (113)
BEVACIZUMAB (110)
ADALIMUMAB (97)
CARBIDOPA\LEVODOPA (81)
PREDNISONE (70)
CISPLATIN (68)
OXALIPLATIN (68)
DEXAMETHASONE (66)
CAPECITABINE (64)
RITUXIMAB (59)
Which METHOTREXATE Alternatives Have Lower Gastric perforation Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA