Does METHOTREXATE Cause Generalised tonic-clonic seizure? 247 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 247 reports of Generalised tonic-clonic seizure have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
247
Reports of Generalised tonic-clonic seizure with METHOTREXATE
0.1%
of all METHOTREXATE reports
45
Deaths
150
Hospitalizations
How Dangerous Is Generalised tonic-clonic seizure From METHOTREXATE?
Of the 247 reports, 45 (18.2%) resulted in death, 150 (60.7%) required hospitalization, and 35 (14.2%) were considered life-threatening.
Is Generalised tonic-clonic seizure Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 247 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Generalised tonic-clonic seizure?
LEVETIRACETAM (2,276)
LACOSAMIDE (918)
LAMOTRIGINE (863)
BUPROPION (686)
TRAMADOL (496)
VENLAFAXINE (427)
CARBAMAZEPINE (377)
VALPROIC ACID (351)
LIDOCAINE (308)
PHENYTOIN (307)
Which METHOTREXATE Alternatives Have Lower Generalised tonic-clonic seizure Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA