Does METHOTREXATE Cause Lethargy? 563 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 563 reports of Lethargy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.2% of all adverse event reports for METHOTREXATE.
563
Reports of Lethargy with METHOTREXATE
0.2%
of all METHOTREXATE reports
56
Deaths
216
Hospitalizations
How Dangerous Is Lethargy From METHOTREXATE?
Of the 563 reports, 56 (9.9%) resulted in death, 216 (38.4%) required hospitalization, and 44 (7.8%) were considered life-threatening.
Is Lethargy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 563 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Lethargy?
DULOXETINE (1,682)
ADALIMUMAB (828)
LENALIDOMIDE (585)
GABAPENTIN (496)
AMLODIPINE (466)
TREPROSTINIL (460)
OXYCODONE (452)
MORPHINE (445)
LEVOTHYROXINE (419)
PREGABALIN (419)
Which METHOTREXATE Alternatives Have Lower Lethargy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA