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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Lethargy: Which Medications Cause It? (38,697 Reports Across 1,115 Drugs)

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Lethargy has been reported as an adverse event with 1,115 different drugs in the FDA's FAERS database, with 38,697 total reports. 2,185 of these reports resulted in death.The drugs most commonly associated with Lethargy are DULOXETINE, ADALIMUMAB, and LENALIDOMIDE.

38,697
Total Reports
1,115
Drugs Involved
2,185
Deaths
12,296
Hospitalizations
53.2 yrs
Average Patient Age
57.7% / 42.3%
Female / Male

Which Drugs Cause Lethargy Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
DULOXETINE 1,682 3.2% 14 231 33
ADALIMUMAB 828 0.2% 13 259 7
LENALIDOMIDE 585 0.2% 38 168 7
METHOTREXATE 563 0.2% 56 216 44
GABAPENTIN 496 0.7% 17 208 25
AMLODIPINE 466 0.7% 60 268 97
TREPROSTINIL 460 0.5% 35 187 13
OXYCODONE 452 0.2% 62 214 25
MORPHINE 445 0.4% 51 193 45
LEVOTHYROXINE 419 0.7% 12 81 8
PREGABALIN 419 0.4% 7 141 19
ACETAMINOPHEN 402 0.3% 40 216 91
ETANERCEPT 381 0.1% 1 54 4
SACUBITRIL\VALSARTAN 375 0.3% 14 76 13
PIMAVANSERIN 370 0.8% 44 85 3
OLANZAPINE 369 0.7% 8 214 20
BACLOFEN 365 1.4% 14 223 37
DUPILUMAB 358 0.1% 2 27 2
SODIUM OXYBATE 355 0.6% 2 108 0
CLONAZEPAM 351 0.9% 15 138 49

View all 1,115 drugs →

Top 3 Drugs Associated With Lethargy

1,682 reports
828 reports
585 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)