Does METHOTREXATE Cause Mental status changes? 352 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 352 reports of Mental status changes have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
352
Reports of Mental status changes with METHOTREXATE
0.1%
of all METHOTREXATE reports
78
Deaths
258
Hospitalizations
How Dangerous Is Mental status changes From METHOTREXATE?
Of the 352 reports, 78 (22.2%) resulted in death, 258 (73.3%) required hospitalization, and 50 (14.2%) were considered life-threatening.
Is Mental status changes Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 352 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Mental status changes?
BACLOFEN (600)
GABAPENTIN (427)
METFORMIN (371)
CLOZAPINE (361)
PREDNISONE (357)
DUPILUMAB (354)
TACROLIMUS (339)
LENALIDOMIDE (316)
MORPHINE (310)
OXYCODONE (309)
Which METHOTREXATE Alternatives Have Lower Mental status changes Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA