Mental status changes: Which Medications Cause It? (16,666 Reports Across 740 Drugs)
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Mental status changes has been reported as an adverse event with 740 different drugs in the FDA's FAERS database, with 16,666 total reports. 2,291 of these reports resulted in death.The drugs most commonly associated with Mental status changes are BACLOFEN, GABAPENTIN, and METFORMIN.
16,666
Total Reports
740
Drugs Involved
2,291
Deaths
11,535
Hospitalizations
55.0 yrs
Average Patient Age
50.9% / 49.1%
Female / Male
Which Drugs Cause Mental status changes Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| BACLOFEN | 600 | 2.3% | 15 | 462 | 104 |
| GABAPENTIN | 427 | 0.6% | 24 | 319 | 52 |
| METFORMIN | 371 | 0.4% | 29 | 347 | 144 |
| CLOZAPINE | 361 | 0.4% | 15 | 322 | 24 |
| PREDNISONE | 357 | 0.2% | 94 | 266 | 68 |
| DUPILUMAB | 354 | 0.1% | 0 | 8 | 0 |
| METHOTREXATE | 352 | 0.1% | 78 | 258 | 50 |
| TACROLIMUS | 339 | 0.4% | 94 | 250 | 92 |
| LENALIDOMIDE | 316 | 0.1% | 65 | 216 | 11 |
| MORPHINE | 310 | 0.3% | 40 | 209 | 40 |
| OXYCODONE | 309 | 0.2% | 26 | 211 | 34 |
| ACETAMINOPHEN | 305 | 0.2% | 57 | 264 | 88 |
| BUPROPION | 286 | 0.8% | 13 | 223 | 45 |
| AMLODIPINE | 284 | 0.4% | 34 | 258 | 132 |
| QUETIAPINE | 268 | 0.4% | 12 | 227 | 52 |
| DEXAMETHASONE | 265 | 0.2% | 49 | 216 | 28 |
| HYDROMORPHONE | 254 | 0.3% | 25 | 173 | 31 |
| CYCLOPHOSPHAMIDE | 231 | 0.2% | 58 | 174 | 25 |
| LEVETIRACETAM | 226 | 0.4% | 12 | 180 | 53 |
| CALCIUM\DEXTROSE\MAGNESIUM\SODIUM\SODIUM | 215 | 0.2% | 47 | 205 | 2 |