Does METHOTREXATE Cause Metabolic acidosis? 263 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 263 reports of Metabolic acidosis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
263
Reports of Metabolic acidosis with METHOTREXATE
0.1%
of all METHOTREXATE reports
131
Deaths
209
Hospitalizations
How Dangerous Is Metabolic acidosis From METHOTREXATE?
Of the 263 reports, 131 (49.8%) resulted in death, 209 (79.5%) required hospitalization, and 92 (35.0%) were considered life-threatening.
Is Metabolic acidosis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 263 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Metabolic acidosis?
METFORMIN (5,236)
ACETAMINOPHEN (2,538)
AMLODIPINE (1,202)
IBUPROFEN (974)
EMPAGLIFLOZIN (572)
TACROLIMUS (491)
VENLAFAXINE (460)
FLUOXETINE (437)
ESOMEPRAZOLE (430)
FUROSEMIDE (413)
Which METHOTREXATE Alternatives Have Lower Metabolic acidosis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA