Does METHOTREXATE Cause Microcephaly? 26 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 26 reports of Microcephaly have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
26
Reports of Microcephaly with METHOTREXATE
0.0%
of all METHOTREXATE reports
1
Deaths
1
Hospitalizations
How Dangerous Is Microcephaly From METHOTREXATE?
Of the 26 reports, 1 (3.8%) resulted in death, 1 (3.8%) required hospitalization.
Is Microcephaly Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 26 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Microcephaly?
LAMOTRIGINE (74)
VALPROATE (57)
METOPROLOL (52)
LEVETIRACETAM (46)
VENLAFAXINE (42)
VALPROIC ACID (38)
ACETAMINOPHEN (37)
CARBAMAZEPINE (36)
LEVOTHYROXINE (34)
METFORMIN (33)
Which METHOTREXATE Alternatives Have Lower Microcephaly Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA