Does METHOTREXATE Cause Osteomyelitis? 673 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 673 reports of Osteomyelitis have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
673
Reports of Osteomyelitis with METHOTREXATE
0.3%
of all METHOTREXATE reports
25
Deaths
283
Hospitalizations
How Dangerous Is Osteomyelitis From METHOTREXATE?
Of the 673 reports, 25 (3.7%) resulted in death, 283 (42.1%) required hospitalization, and 51 (7.6%) were considered life-threatening.
Is Osteomyelitis Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 673 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Osteomyelitis?
CANAGLIFLOZIN (2,146)
DENOSUMAB (701)
ADALIMUMAB (636)
ETANERCEPT (488)
ZOLEDRONIC ACID (419)
TOCILIZUMAB (400)
RITUXIMAB (360)
PREDNISONE (350)
LEFLUNOMIDE (332)
ABATACEPT (320)
Which METHOTREXATE Alternatives Have Lower Osteomyelitis Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA