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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Osteomyelitis: Which Medications Cause It? (12,171 Reports Across 497 Drugs)

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Osteomyelitis has been reported as an adverse event with 497 different drugs in the FDA's FAERS database, with 12,171 total reports. 787 of these reports resulted in death.The drugs most commonly associated with Osteomyelitis are CANAGLIFLOZIN, DENOSUMAB, and METHOTREXATE.

12,171
Total Reports
497
Drugs Involved
787
Deaths
7,186
Hospitalizations
58.8 yrs
Average Patient Age
50.8% / 49.2%
Female / Male

Which Drugs Cause Osteomyelitis Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
CANAGLIFLOZIN 2,146 8.8% 20 1,807 9
DENOSUMAB 701 0.5% 28 201 7
METHOTREXATE 673 0.3% 25 283 51
ADALIMUMAB 636 0.1% 28 334 13
ETANERCEPT 488 0.1% 11 200 8
ZOLEDRONIC ACID 419 1.3% 41 121 2
TOCILIZUMAB 400 0.4% 8 144 3
RITUXIMAB 360 0.2% 35 173 27
PREDNISONE 350 0.2% 51 192 50
LEFLUNOMIDE 332 0.6% 6 129 19
ABATACEPT 320 0.3% 4 132 2
LENALIDOMIDE 313 0.1% 20 132 4
INFLIXIMAB 312 0.2% 6 133 3
GOLIMUMAB 272 0.4% 3 125 2
ALENDRONATE 257 0.9% 12 186 5
HYDROXYCHLOROQUINE 234 0.4% 3 141 23
TACROLIMUS 213 0.2% 46 163 30
TOFACITINIB 210 0.1% 9 85 1
CERTOLIZUMAB PEGOL 199 0.2% 4 111 7
CANAGLIFLOZIN\METFORMIN 197 12.8% 2 167 1

View all 497 drugs →

Top 3 Drugs Associated With Osteomyelitis

2,146 reports
701 reports
673 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)