Does METHOTREXATE Cause Posterior reversible encephalopathy syndrome? 951 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 951 reports of Posterior reversible encephalopathy syndrome have been filed in association with METHOTREXATE (Methotrexate). This represents 0.4% of all adverse event reports for METHOTREXATE.
951
Reports of Posterior reversible encephalopathy syndrome with METHOTREXATE
0.4%
of all METHOTREXATE reports
76
Deaths
464
Hospitalizations
How Dangerous Is Posterior reversible encephalopathy syndrome From METHOTREXATE?
Of the 951 reports, 76 (8.0%) resulted in death, 464 (48.8%) required hospitalization, and 109 (11.5%) were considered life-threatening.
Is Posterior reversible encephalopathy syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 951 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Posterior reversible encephalopathy syndrome?
TACROLIMUS (1,118)
CYCLOSPORINE (898)
VINCRISTINE (685)
CYCLOPHOSPHAMIDE (658)
MYCOPHENOLATE MOFETIL (621)
PREDNISONE (614)
DEXAMETHASONE (586)
METHYLPREDNISOLONE (579)
PREDNISOLONE (473)
RITUXIMAB (459)
Which METHOTREXATE Alternatives Have Lower Posterior reversible encephalopathy syndrome Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA