Posterior reversible encephalopathy syndrome: Which Medications Cause It? (7,833 Reports Across 390 Drugs)
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Posterior reversible encephalopathy syndrome has been reported as an adverse event with 390 different drugs in the FDA's FAERS database, with 7,833 total reports. 798 of these reports resulted in death.The drugs most commonly associated with Posterior reversible encephalopathy syndrome are TACROLIMUS, METHOTREXATE, and CYCLOSPORINE.
7,833
Total Reports
390
Drugs Involved
798
Deaths
4,602
Hospitalizations
40.7 yrs
Average Patient Age
64.0% / 36.0%
Female / Male
Which Drugs Cause Posterior reversible encephalopathy syndrome Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| TACROLIMUS | 1,118 | 1.2% | 145 | 589 | 202 |
| METHOTREXATE | 951 | 0.4% | 76 | 464 | 109 |
| CYCLOSPORINE | 898 | 1.3% | 124 | 287 | 96 |
| VINCRISTINE | 685 | 0.9% | 51 | 404 | 90 |
| CYCLOPHOSPHAMIDE | 658 | 0.5% | 79 | 365 | 103 |
| MYCOPHENOLATE MOFETIL | 621 | 0.8% | 107 | 320 | 98 |
| PREDNISONE | 614 | 0.4% | 97 | 403 | 144 |
| DEXAMETHASONE | 586 | 0.5% | 60 | 299 | 66 |
| METHYLPREDNISOLONE | 579 | 0.9% | 81 | 284 | 111 |
| PREDNISOLONE | 473 | 0.6% | 64 | 278 | 110 |
| RITUXIMAB | 459 | 0.3% | 77 | 279 | 87 |
| DOXORUBICIN | 424 | 0.5% | 45 | 245 | 55 |
| CYTARABINE | 419 | 0.9% | 33 | 235 | 50 |
| BEVACIZUMAB | 360 | 0.5% | 47 | 234 | 36 |
| ETOPOSIDE | 357 | 0.7% | 77 | 166 | 50 |
| FLUDARABINE | 298 | 1.3% | 55 | 55 | 38 |
| CARBOPLATIN | 293 | 0.4% | 54 | 200 | 47 |
| DAUNORUBICIN | 247 | 2.5% | 10 | 124 | 23 |
| BORTEZOMIB | 206 | 0.4% | 55 | 101 | 43 |
| PACLITAXEL | 204 | 0.3% | 39 | 151 | 19 |