Does METHOTREXATE Cause Pulmonary toxicity? 811 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 811 reports of Pulmonary toxicity have been filed in association with METHOTREXATE (Methotrexate). This represents 0.3% of all adverse event reports for METHOTREXATE.
811
Reports of Pulmonary toxicity with METHOTREXATE
0.3%
of all METHOTREXATE reports
67
Deaths
238
Hospitalizations
How Dangerous Is Pulmonary toxicity From METHOTREXATE?
Of the 811 reports, 67 (8.3%) resulted in death, 238 (29.3%) required hospitalization, and 45 (5.5%) were considered life-threatening.
Is Pulmonary toxicity Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 811 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Pulmonary toxicity?
AMIODARONE (886)
HYDROXYCHLOROQUINE (411)
RITUXIMAB (404)
TOCILIZUMAB (395)
LEFLUNOMIDE (364)
ABATACEPT (359)
ADALIMUMAB (326)
PEMBROLIZUMAB (318)
ETANERCEPT (291)
BLEOMYCIN (263)
Which METHOTREXATE Alternatives Have Lower Pulmonary toxicity Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA