Pulmonary toxicity: Which Medications Cause It? (5,383 Reports Across 270 Drugs)
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Pulmonary toxicity has been reported as an adverse event with 270 different drugs in the FDA's FAERS database, with 5,383 total reports. 944 of these reports resulted in death.The drugs most commonly associated with Pulmonary toxicity are AMIODARONE, METHOTREXATE, and HYDROXYCHLOROQUINE.
5,383
Total Reports
270
Drugs Involved
944
Deaths
2,309
Hospitalizations
62.7 yrs
Average Patient Age
48.8% / 51.2%
Female / Male
Which Drugs Cause Pulmonary toxicity Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| AMIODARONE | 886 | 3.5% | 208 | 519 | 183 |
| METHOTREXATE | 811 | 0.3% | 67 | 238 | 45 |
| HYDROXYCHLOROQUINE | 411 | 0.6% | 16 | 96 | 16 |
| RITUXIMAB | 404 | 0.2% | 61 | 143 | 16 |
| TOCILIZUMAB | 395 | 0.4% | 17 | 102 | 15 |
| LEFLUNOMIDE | 364 | 0.6% | 17 | 101 | 15 |
| ABATACEPT | 359 | 0.3% | 10 | 103 | 12 |
| ADALIMUMAB | 326 | 0.1% | 15 | 112 | 15 |
| PEMBROLIZUMAB | 318 | 0.4% | 35 | 137 | 11 |
| ETANERCEPT | 291 | 0.1% | 16 | 104 | 15 |
| BLEOMYCIN | 263 | 3.8% | 137 | 59 | 27 |
| NIVOLUMAB | 253 | 0.3% | 37 | 111 | 25 |
| SULFASALAZINE | 250 | 0.6% | 17 | 104 | 16 |
| DOXORUBICIN | 248 | 0.3% | 79 | 81 | 18 |
| CYCLOPHOSPHAMIDE | 230 | 0.2% | 75 | 74 | 17 |
| PREDNISONE | 225 | 0.1% | 38 | 91 | 31 |
| PACLITAXEL | 207 | 0.3% | 24 | 107 | 13 |
| CARBOPLATIN | 200 | 0.2% | 49 | 86 | 14 |
| GOLD | 199 | 4.8% | 13 | 86 | 13 |
| MELOXICAM | 192 | 2.2% | 13 | 21 | 13 |