Does METHOTREXATE Cause Spinal compression fracture? 224 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 224 reports of Spinal compression fracture have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
224
Reports of Spinal compression fracture with METHOTREXATE
0.1%
of all METHOTREXATE reports
15
Deaths
96
Hospitalizations
How Dangerous Is Spinal compression fracture From METHOTREXATE?
Of the 224 reports, 15 (6.7%) resulted in death, 96 (42.9%) required hospitalization, and 19 (8.5%) were considered life-threatening.
Is Spinal compression fracture Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 224 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Spinal compression fracture?
DENOSUMAB (814)
ADALIMUMAB (393)
LENALIDOMIDE (362)
ALENDRONATE (239)
PREDNISOLONE (175)
ROMOSOZUMAB-AQQG (164)
TERIPARATIDE (164)
DEXAMETHASONE (161)
ETANERCEPT (160)
EMTRICITABINE\TENOFOVIR DISOPROXIL (151)
Which METHOTREXATE Alternatives Have Lower Spinal compression fracture Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA