Spinal compression fracture: Which Medications Cause It? (6,241 Reports Across 369 Drugs)
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Spinal compression fracture has been reported as an adverse event with 369 different drugs in the FDA's FAERS database, with 6,241 total reports. 382 of these reports resulted in death.The drugs most commonly associated with Spinal compression fracture are DENOSUMAB, ADALIMUMAB, and LENALIDOMIDE.
6,241
Total Reports
369
Drugs Involved
382
Deaths
3,018
Hospitalizations
67.2 yrs
Average Patient Age
67.2% / 32.8%
Female / Male
Which Drugs Cause Spinal compression fracture Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| DENOSUMAB | 814 | 0.6% | 11 | 159 | 4 |
| ADALIMUMAB | 393 | 0.1% | 6 | 166 | 2 |
| LENALIDOMIDE | 362 | 0.1% | 17 | 188 | 4 |
| ALENDRONATE | 239 | 0.9% | 15 | 207 | 0 |
| METHOTREXATE | 224 | 0.1% | 15 | 96 | 19 |
| PREDNISOLONE | 175 | 0.2% | 18 | 105 | 11 |
| ROMOSOZUMAB-AQQG | 164 | 1.4% | 0 | 57 | 0 |
| TERIPARATIDE | 164 | 0.2% | 2 | 48 | 0 |
| DEXAMETHASONE | 161 | 0.1% | 17 | 111 | 6 |
| ETANERCEPT | 160 | 0.0% | 2 | 59 | 0 |
| EMTRICITABINE\TENOFOVIR DISOPROXIL | 151 | 0.4% | 2 | 28 | 0 |
| PREDNISONE | 142 | 0.1% | 10 | 74 | 6 |
| TOCILIZUMAB | 137 | 0.1% | 8 | 39 | 5 |
| RITUXIMAB | 127 | 0.1% | 10 | 72 | 3 |
| ZOLEDRONIC ACID | 126 | 0.4% | 12 | 54 | 8 |
| TOFACITINIB | 108 | 0.1% | 3 | 39 | 3 |
| ABATACEPT | 86 | 0.1% | 2 | 51 | 1 |
| EFAVIRENZ\EMTRICITABINE\TENOFOVIR DISOPROXIL | 74 | 0.4% | 1 | 7 | 0 |
| UPADACITINIB | 73 | 0.1% | 3 | 39 | 0 |
| BORTEZOMIB | 71 | 0.2% | 6 | 44 | 5 |