Does METHOTREXATE Cause Systemic inflammatory response syndrome? 158 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 158 reports of Systemic inflammatory response syndrome have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
158
Reports of Systemic inflammatory response syndrome with METHOTREXATE
0.1%
of all METHOTREXATE reports
40
Deaths
95
Hospitalizations
How Dangerous Is Systemic inflammatory response syndrome From METHOTREXATE?
Of the 158 reports, 40 (25.3%) resulted in death, 95 (60.1%) required hospitalization, and 30 (19.0%) were considered life-threatening.
Is Systemic inflammatory response syndrome Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 158 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Systemic inflammatory response syndrome?
DOXORUBICIN (161)
CYCLOPHOSPHAMIDE (153)
CYTARABINE (153)
METHYLPREDNISOLONE (117)
ADALIMUMAB (107)
RITUXIMAB (106)
PREDNISOLONE (99)
VINCRISTINE (97)
MYCOPHENOLATE MOFETIL (95)
PREDNISONE (95)
Which METHOTREXATE Alternatives Have Lower Systemic inflammatory response syndrome Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA