Does METHOTREXATE Cause Toothache? 275 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 275 reports of Toothache have been filed in association with METHOTREXATE (Methotrexate). This represents 0.1% of all adverse event reports for METHOTREXATE.
275
Reports of Toothache with METHOTREXATE
0.1%
of all METHOTREXATE reports
5
Deaths
82
Hospitalizations
How Dangerous Is Toothache From METHOTREXATE?
Of the 275 reports, 5 (1.8%) resulted in death, 82 (29.8%) required hospitalization, and 24 (8.7%) were considered life-threatening.
Is Toothache Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 275 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Toothache?
DENOSUMAB (929)
ADALIMUMAB (625)
DUPILUMAB (607)
ETANERCEPT (569)
TOCILIZUMAB (397)
LENALIDOMIDE (330)
ZOLEDRONIC ACID (288)
TERIPARATIDE (270)
NAPROXEN (260)
INFLIXIMAB (219)
Which METHOTREXATE Alternatives Have Lower Toothache Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA