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Important: This site presents data from the FDA Adverse Event Reporting System (FAERS). A report does not mean the drug caused the event. Full disclaimer.

Toothache: Which Medications Cause It? (12,772 Reports Across 495 Drugs)

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Toothache has been reported as an adverse event with 495 different drugs in the FDA's FAERS database, with 12,772 total reports. 193 of these reports resulted in death.The drugs most commonly associated with Toothache are DENOSUMAB, ADALIMUMAB, and DUPILUMAB.

12,772
Total Reports
495
Drugs Involved
193
Deaths
2,051
Hospitalizations
56.7 yrs
Average Patient Age
71.3% / 28.7%
Female / Male

Which Drugs Cause Toothache Most Often?

Drug Reports % of Drug Reports Deaths Hosp. Life-Threat.
DENOSUMAB 929 0.6% 4 98 4
ADALIMUMAB 625 0.1% 1 103 2
DUPILUMAB 607 0.2% 0 16 0
ETANERCEPT 569 0.2% 0 32 0
TOCILIZUMAB 397 0.4% 2 52 10
LENALIDOMIDE 330 0.1% 2 20 0
ZOLEDRONIC ACID 288 0.9% 15 66 6
METHOTREXATE 275 0.1% 5 82 24
TERIPARATIDE 270 0.4% 0 7 0
NAPROXEN 260 0.5% 0 14 1
INFLIXIMAB 219 0.2% 0 48 2
RITUXIMAB 191 0.1% 6 53 10
TOFACITINIB 189 0.1% 2 30 3
METFORMIN 182 0.2% 0 12 4
SECUKINUMAB 182 0.1% 0 36 14
PALBOCICLIB 177 0.2% 4 24 2
INSULIN GLARGINE 176 0.2% 0 1 2
INSULIN HUMAN 159 0.6% 0 7 0
BUPRENORPHINE\NALOXONE 156 0.7% 2 27 7
NALTREXONE 151 0.6% 2 3 0

View all 495 drugs →

Top 3 Drugs Associated With Toothache

929 reports
625 reports
607 reports

Related Side Effects

Drug ineffective (1,049,718) Off label use (762,782) Death (660,423) Fatigue (599,248) Nausea (562,301) Diarrhoea (491,550) Pain (471,975) Headache (460,069) Dyspnoea (409,496) Dizziness (352,922)