Does METHOTREXATE Cause Toxic leukoencephalopathy? 82 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 82 reports of Toxic leukoencephalopathy have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
82
Reports of Toxic leukoencephalopathy with METHOTREXATE
0.0%
of all METHOTREXATE reports
5
Deaths
42
Hospitalizations
How Dangerous Is Toxic leukoencephalopathy From METHOTREXATE?
Of the 82 reports, 5 (6.1%) resulted in death, 42 (51.2%) required hospitalization, and 12 (14.6%) were considered life-threatening.
Is Toxic leukoencephalopathy Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 82 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Toxic leukoencephalopathy?
OXYCODONE (122)
FLUOROURACIL (58)
FENTANYL (51)
CAPECITABINE (45)
CYCLOSPORINE (44)
FLUDARABINE (43)
MORPHINE (42)
OXALIPLATIN (42)
METHADONE (35)
COCAINE (34)
Which METHOTREXATE Alternatives Have Lower Toxic leukoencephalopathy Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA