Does METHOTREXATE Cause Vitamin b12 deficiency? 101 Reports in FDA Database
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According to the FDA Adverse Event Reporting System (FAERS), 101 reports of Vitamin b12 deficiency have been filed in association with METHOTREXATE (Methotrexate). This represents 0.0% of all adverse event reports for METHOTREXATE.
101
Reports of Vitamin b12 deficiency with METHOTREXATE
0.0%
of all METHOTREXATE reports
13
Deaths
59
Hospitalizations
How Dangerous Is Vitamin b12 deficiency From METHOTREXATE?
Of the 101 reports, 13 (12.9%) resulted in death, 59 (58.4%) required hospitalization, and 17 (16.8%) were considered life-threatening.
Is Vitamin b12 deficiency Listed in the Official Label?
This adverse event is not currently listed in the official FDA drug label for METHOTREXATE. However, 101 reports have been filed with the FAERS database.
What Other Side Effects Does METHOTREXATE Cause?
Drug ineffective (70,142)
Rheumatoid arthritis (29,254)
Off label use (24,020)
Pain (23,773)
Drug intolerance (22,555)
Arthralgia (21,831)
Fatigue (19,885)
Nausea (18,715)
Joint swelling (17,657)
Drug hypersensitivity (16,677)
What Other Drugs Cause Vitamin b12 deficiency?
METFORMIN (504)
ADALIMUMAB (148)
OMEPRAZOLE (125)
ESOMEPRAZOLE (111)
PANTOPRAZOLE (107)
ASPIRIN (92)
ETANERCEPT (82)
CARBIDOPA\LEVODOPA (76)
PREDNISONE (75)
RITUXIMAB (71)
Which METHOTREXATE Alternatives Have Lower Vitamin b12 deficiency Risk?
METHOTREXATE vs METHOXSALEN
METHOTREXATE vs METHOXY POLYETHYLENE GLYCOL-EPOETIN BETA
METHOTREXATE vs METHYL ALCOHOL
METHOTREXATE vs METHYLCOBALAMIN
METHOTREXATE vs METHYLDOPA