Vitamin b12 deficiency: Which Medications Cause It? (2,876 Reports Across 297 Drugs)
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Vitamin b12 deficiency has been reported as an adverse event with 297 different drugs in the FDA's FAERS database, with 2,876 total reports. 91 of these reports resulted in death.The drugs most commonly associated with Vitamin b12 deficiency are METFORMIN, ADALIMUMAB, and OMEPRAZOLE.
2,876
Total Reports
297
Drugs Involved
91
Deaths
1,210
Hospitalizations
58.5 yrs
Average Patient Age
61.4% / 38.6%
Female / Male
Which Drugs Cause Vitamin b12 deficiency Most Often?
| Drug | Reports | % of Drug Reports | Deaths | Hosp. | Life-Threat. |
|---|---|---|---|---|---|
| METFORMIN | 504 | 0.6% | 1 | 293 | 20 |
| ADALIMUMAB | 148 | 0.0% | 0 | 62 | 2 |
| OMEPRAZOLE | 125 | 0.1% | 4 | 49 | 0 |
| ESOMEPRAZOLE | 111 | 0.2% | 0 | 19 | 20 |
| PANTOPRAZOLE | 107 | 0.1% | 0 | 54 | 8 |
| METHOTREXATE | 101 | 0.0% | 13 | 59 | 17 |
| ASPIRIN | 92 | 0.1% | 1 | 34 | 21 |
| ETANERCEPT | 82 | 0.0% | 0 | 12 | 14 |
| CARBIDOPA\LEVODOPA | 76 | 0.1% | 3 | 44 | 0 |
| PREDNISONE | 75 | 0.1% | 1 | 23 | 20 |
| RITUXIMAB | 71 | 0.0% | 8 | 16 | 28 |
| USTEKINUMAB | 57 | 0.1% | 0 | 20 | 0 |
| DEXAMETHASONE | 55 | 0.0% | 0 | 23 | 1 |
| LENALIDOMIDE | 53 | 0.0% | 0 | 12 | 3 |
| VEDOLIZUMAB | 50 | 0.1% | 0 | 19 | 0 |
| FINGOLIMOD | 49 | 0.1% | 0 | 14 | 0 |
| ATORVASTATIN | 48 | 0.1% | 0 | 31 | 2 |
| PREGABALIN | 48 | 0.1% | 0 | 4 | 20 |
| SODIUM OXYBATE | 47 | 0.1% | 0 | 7 | 0 |
| ALENDRONATE | 45 | 0.2% | 8 | 43 | 0 |